So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Dawange, Monali A.; Urmode, Tukaram D.; Khan, Ayesha; Kusurkar, Radhika S. researched the compound: 5-Methoxy-1H-indole-2-carbaldehyde( cas:21778-81-4 ).Electric Literature of C10H9NO2.They published the article 《Acid Catalyzed Synthesis of Spiroindolone Scaffolds by Iso-Pictet-Spengler Spirocyclization and Evaluation of their Antibacterial Activity》 about this compound( cas:21778-81-4 ) in ChemistrySelect. Keywords: spiroindolone preparation antibacterial; isatin isotryptamine iso Pictet Spengler spirocyclization acetic acid catalyst. We’ll tell you more about this compound (cas:21778-81-4).
Acetic acid catalyzed synthesis of new spiroindolones (tetrahydrospiro-γ-carbolines) was achieved in good yield by iso-Pictet Spengler spirocyclization of substituted isotryptamines with isatins. All the compounds were screened for antibacterial activities against S. aureus, E. coli, P. aeruginosa and S. typhi bacteria. The preliminary antibacterial study indicated that compounds bearing halo substituent showed potent inhibitory activity towards S. typhi and P. aeruginosa and moderate activities towards S. aureus and E. coli.
In some applications, this compound(21778-81-4)Electric Literature of C10H9NO2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem