The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Methoxy-1H-indole-2-carbaldehyde( cas:21778-81-4 ) is researched.Name: 5-Methoxy-1H-indole-2-carbaldehyde.Zhang, Lei; Zhao, Fei; Zheng, Mingyue; Zhai, Yun; Liu, Hong published the article 《Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating》 about this compound( cas:21778-81-4 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: three distinct set indole heterocycle preparation; Ugi adduct microwave heating. Let’s learn more about this compound (cas:21778-81-4).
Three distinct sets of indole-based heterocycles, e.g. I, II and III, were rapidly and selectively synthesized from the same set of Ugi-adducts, e.g. IV, under microwave heating in a reaction-condition-controlled manner. Notably, an unprecedented metal-free intramol. sp3-hybridized C-H arylation using only cesium carbonate was discovered.
There are many compounds similar to this compound(21778-81-4)Name: 5-Methoxy-1H-indole-2-carbaldehyde. if you want to know more, you can check out my other articles. I hope it will help you,maybe you’ll find some useful information.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem