In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Efficient selective synthesis of 2-substituted indoles from complex-base-promoted arynic cyclizations, published in 1997-10-07, which mentions a compound: 21778-81-4, mainly applied to indole preparation arynic cyclization; imine methyl ketone preparation cyclization; thiopyranoindole tetrahydro preparation ring cleavage; mercaptopropylindole preparation, COA of Formula: C10H9NO2.
Indoles I [R = 5-MeO, 5-Me, 5-F, 7-Me, 5-MeO, 5-Cl, H; R1 = H, MeO; R2 = n-Pr, i-Pr, allyl, (CH2)2NEt2, (CH2)2NMe2, (CH2)2OEt, MeO] were efficiently obtained by selective arynic cyclization of halogenated aryl imines, e.g. 3,4-Cl(MeO)C6H3N:CMeCH2CH2CH2Me, in the presence of the complex-base NaNH2-Me3CONa. (Mercaptopropyl)indoles II (R = 5-OH, 7-OH; R3 = H, Me, CH2Ph, CH2CO2Et) were prepared by PhCH2SH-AlCl3 promoted opening of tetrahydrothiopyranoindoles which were also obtained from arynic cyclization of imines.
I hope my short article helps more people learn about this compound(5-Methoxy-1H-indole-2-carbaldehyde)COA of Formula: C10H9NO2. Apart from the compound(21778-81-4), you can read my other articles to know other related compounds.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem