Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 21778-81-4, is researched, Molecular C10H9NO2, about Pd-catalyzed cascade allylic alkylation and dearomatization reactions of indoles with vinyloxirane, the main research direction is tetrahydrocarboline preparation; indolylmethyl malonate vinyloxirane cascade ring opening allylic alkylation palladium; spiroindolenine preparation diastereoselective; indolylethyl malonate vinyloxirane cascade ring opening allylic dearomatization palladium.Category: pyridazine.
A palladium-catalyzed cascade allylic alkylation reaction of di-Me malonate tethered indoles with vinyloxirane was developed through intramol. nucleophilic ring-opening of vinyloxirane followed by subsequent intramol. Friedel-Crafts type allylic alkylation or allylic dearomatization. This protocol provided an efficient method to synthesize structurally diverse tetrahydrocarbolines e.g., I, and spiroindolenine derivatives e.g., II, under mild conditions.
Here is just a brief introduction to this compound(21778-81-4)Category: pyridazine, more information about the compound(5-Methoxy-1H-indole-2-carbaldehyde) is in the article, you can click the link below.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem