The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-Methoxy-1H-indole-2-carbaldehyde(SMILESS: O=CC(N1)=CC2=C1C=CC(OC)=C2,cas:21778-81-4) is researched.Recommanded Product: 148-51-6. The article 《Oxidation by silver carbonate on celite. XV. Heterocyclic alcohols》 in relation to this compound, is published in Journal of Heterocyclic Chemistry. Let’s take a look at the latest research on this compound (cas:21778-81-4).
Oxidation of primary and secondary alcs. in heterocyclic series by AgCO3 absorbed on Celite gave aldehydes or ketones with excellent yields. Also oxidized were the alcs. containing the furan, pyrrole, thiophene, pyridine, or indole nucleus. The oxidation of codeine and of dihydrocodeine also was studied. Although the AgCO3 did not react with dihydrocodeine, the oxidation occurred using Ag2CO5-Celite. The yield for codeinone is better than 91%. Tetrahydrofurfuryl alc. and 2-hydroxymethyltetrahydropyran were slowly degraded to γ-butyrolactone and δ-valerolactone, resp.
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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem