In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called 2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists, published in 1998-09-10, which mentions a compound: 21778-81-4, mainly applied to melatonin receptor antagonist agonist, Product Details of 21778-81-4.
The synthesis of several novel indole melatonin analogs substituted at the 2-position with acylaminomethyl, acylaminoethyl, or acylaminopropyl side chains is reported. Using a novel in vitro functional assay (specific binding of [35S]GTPγS), the authors showed that several of these compounds exhibited partial agonist, antagonist, and inverse agonist activity. Binding and functional assays were performed on cloned human MT1 receptor. Structure-activity relation considerations indicate that N-[1-aryl-2-(4-methoxy-1H-indol-2-yl)(C1-C2)alkyl]alkanamides represent a lead structure for this type of ligands.
Compound(21778-81-4)Product Details of 21778-81-4 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methoxy-1H-indole-2-carbaldehyde), if you are interested, you can check out my other related articles.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem