Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Comparative Study, Article, Bioorganic & Medicinal Chemistry Letters called Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors, Author is Caldwell, Charles G.; Chen, Ping; He, Jiafang; Parmee, Emma R.; Leiting, Barbara; Marsilio, Frank; Patel, Reshma A.; Wu, Joseph K.; Eiermann, George J.; Petrov, Aleksandr; He, Huaibing; Lyons, Kathryn A.; Thornberry, Nancy A.; Weber, Ann E., which mentions a compound: 136725-55-8, SMILESS is Cl.F[C@@H]1CCNC1, Molecular C4H9ClFN, HPLC of Formula: 136725-55-8.
Amides derived from fluorinated pyrrolidines and 4-substituted cyclohexylglycine analogs have been prepared and evaluated as inhibitors of dipeptidyl dipeptidase IV (DP-IV). Analogs which incorporated (S)-3-fluoropyrrolidine showed good selectivity for DP-IV over quiescent cell proline dipeptidase (QPP). Amide I had good pharmacokinetic properties and was orally active in an oral glucose tolerance test in lean mice.
There is still a lot of research devoted to this compound(SMILES：Cl.F[C@@H]1CCNC1)HPLC of Formula: 136725-55-8, and with the development of science, more effects of this compound(136725-55-8) can be discovered.
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem