Extracurricular laboratory: Synthetic route of 21778-81-4

Here is a brief introduction to this compound(21778-81-4)COA of Formula: C10H9NO2, if you want to know about other compounds related to this compound(21778-81-4), you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists, published in 2014-08-01, which mentions a compound: 21778-81-4, Name is 5-Methoxy-1H-indole-2-carbaldehyde, Molecular C10H9NO2, COA of Formula: C10H9NO2.

5-Oxo-ETE is the most potent eosinophil chemoattractant among lipid mediators. We have developed two 5-oxo-ETE receptor antagonists. In the course of the work, we have developed a procedure to selectively introduce a cis and trans double bond in an alkyl side chain. Reacting indolecarboxaldehydes with alkyl ylides using the Li base affords the trans olefins, whereas using the K base yields the cis olefins.

Here is a brief introduction to this compound(21778-81-4)COA of Formula: C10H9NO2, if you want to know about other compounds related to this compound(21778-81-4), you can read my other articles.

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2 – PubChem