With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.33097-39-1,3,6-Difluoropyridazine,as a common compound, the synthetic route is as follows.
A mixture of 3,6-difluoropyridazine (60.3 mmol) and 25 mL of ammonia was added to the tube and the reaction was allowed to proceed at 70 C for 2 hours. After cooling, the resulting precipitate was collected by filtration, washed with water and dried to give 4.28 g of the title compound., 33097-39-1
The synthetic route of 33097-39-1 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; CHIA TAI TIANQING (CTTQ) Pharmaceutical Co., Ltd.; Jiao, Dengming; Liang, Zhi; Hu, Yuandong; Hu, Quan; Zhang, Qinghui; Han, YongXin; Wang, Huan; Peng, Yong; Kong, Fansheng; Luo, Hong; (49 pag.)CN103130791; (2016); B;,
Pyridazine – Wikipedia
Pyridazine | C4H4N2 – PubChem