108784-42-5, 6-Fluoropyridazin-3-amine is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
6-Fiuoro-pyridazin-3-ylamine [108784-42-5] (10 g, 89 mmol) was combined with a 50% (wjv)aqueous solution of chloroacetaldehyde [107-20-0] (23 ml, 177 mmol) inn-butanol (150 ml) and stirred at reflux for 1h. The cooled reaction solution was reduced in volume and diluted with diethylether to precipitate a brown solid, which was collected by filtration, to yield 12.0 g. LRMS (ESI) mjz138.0 [(M+H)J+, calc’d for CGH4FN3: 137.12.
108784-42-5, The synthetic route of 108784-42-5 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; LEXICON PHARMACEUTICALS, INC.; BI, Yingzhi; CARSON, Kenneth Gordon; CIANCHETTA, Giovanni; GREEN, Michael Alan; KUMI, Godwin; LIANG, Zhi; LIU, Ying Jade; MAIN, Alan; ZHANG, Yulian; ZIPP, Glenn Gregory; WO2013/134219; (2013); A1;,
Pyridazine – Wikipedia
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