Application In Synthesis of 4,5-Dichloro-3(2H)-pyridazinone, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 932-22-9, Name is 4,5-Dichloro-3(2H)-pyridazinone, molecular formula is C4H2Cl2N2O. In a Article，once mentioned of 932-22-9
Our previous work on pyridazinone-arylpiperazine derivatives suggested some structural features that a compound should have to show high affinity and good selectivity for alpha1 adrenoceptors (AR) with respect to alpha2-AR. Accordingly, two classes of new alkoxyphenylpiperazinylheptylpyridazinones were designed and synthesized to evaluate the effect of the alkoxy substituent on affinity and selectivity. As expected, affinity increased with larger alkoxy groups. Affinity values are all comparable with that of the reference compound (prazosin), with the exception of compound 1c found 4.5-fold more active than prazosin.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2296 – PubChem