88491-61-6, Name is 3-Bromopyridazine, belongs to pyridazine compound, is a common compound. Application of 88491-61-6In an article, once mentioned the new application about 88491-61-6.
Herein, a general, solvent-free and straightforward thiomethylation of electron deficient heterocycles using BF3·SMe2 as a dual thiomethyl source and Lewis acidic activator is presented. A range of heterocycles including pyrimidine, pyrazine, pyridazine, thiazole and purine derivatives were successfully substituted using this method. An unexpected reductive property of BF3·SMe2 towards nitropyridines was also discovered including an intriguing tandem reduction/SMe insertion process in certain substrates. Notable features of the present work include its convenience and use of a non-malodorous reagent while the discovery of novel chemical transformations using BF3·SMe2 provides fundamental new insights into the reactivity of this commonly employed reagent.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 88491-61-6 is helpful to your research. Application of 88491-61-6
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2153 – PubChem