Modeling chemical reactions helps engineers virtually understand the chemistry, optimal size and design of the system, and how it interacts with other physics that may come into play. Application In Synthesis of 3,6-Dichloropyridazine
Hepatocellular carcinoma is one of the most common kind of cancers in clinical, and its clinical treatment is quite difficult. The latest research suggests that pyridazinone with a novel molecular skeleton shows excellent activity against hepatocellular carcinoma in vitro and in vivo. Considering YHHU-759 as the leading compound for reasonable structure modification, a series of 3,3?-bipyridazine derivatives including 8 novel compounds in this study were designed, synthesized and screened for their anti-hepatoma activities against liver cancer cell lines SMMC-7721, BEL-7402 and QGY-7703 in vitro. The result shows that all of the 3,3?-bipyridazine derivatives have good anti-hepatoma activities.
Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.Read on for other articles about 141-30-0Application In Synthesis of 3,6-Dichloropyridazine
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1974 – PubChem