18591-82-7, Name is 6-Methylpyridazin-3-amine, belongs to pyridazine compound, is a common compound. Electric Literature of 18591-82-7In an article, once mentioned the new application about 18591-82-7.
On reacting the 3-aminopyridazines 1a,d,e with dimethyl acetylenedicarboxylate (DMAD), the pyrimido[1,2-b]pyridazin-2(2H)-ones 2e-g, whereas starting from 1f, the 4(4H)-ones 5a and 3b,d were prepared. In the 2(2H)-one series, the reactions of 2b with various amino compounds resulted in various types of products. The reaction of N-methylaminopyridazines 1g,h with DMAD led to the endo-N-substituted derivatives 8a,b, whereas 1h with diethyl ethoxymethylenemalonate (DEM) gave the exo-N-substituted compound 1k. The constitution of the compounds was proved by spectroscopic and chemical evidences.
The result showed that such a combination of chemo- and biocatalysis improved the catalytic yield more than two times compared with that of sole metal catalysis.I hope my blog about 18591-82-7 is helpful to your research.Electric Literature of 18591-82-7
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N239 – PubChem