Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. category: pyridazine
The present invention provides a process for manufacturing 6-oxo-1 H-pyridazine-4-carboxylic acid 5 comprising – (a) reacting dimethyl 2-methylenebutanedioate with hydrazine to obtain methyl 6- oxohexahydropyridazine-4-carboxylate 11; – (b) oxidizing methyl 6-oxohexahydropyridazine-4-carboxylate 11 with a suitable oxidizing agent to methyl 6-oxo-1 H-pyridazine-4-carboxylate 4a; – (c) isolating methyl 6-oxo-1 H-pyridazine-4-carboxylate 4a; – (d) hydrolyzing methyl 6-oxo-1 H-pyridazine-4-carboxylate 4a in the presence of an aqueous base or acid to the 6-oxo-1 H-pyridazine-4-carboxylic acid 5.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2005 – PubChem