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A number of 3-deoxy-DL-prumycin analogues containing one or more amino acid moieties were synthesized.Key intermediate 2 afforded ester analogues by coupling with H-D- or L-Ala-OH, while intermediates 6 and 9 afforded amide analogues by coupling with H-D-Ala-D-Ala-OH, H-D-Ala-OH, 2-amino-4,4-dichlorobutanoic acid and acetic acid.The antifungal activity of the analogues against various phytopathogenic fungi was measured. – Key Words: 3-Deoxyprumycin / Amino acids / Peptides / Antifungal agents
Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 20375-65-9 is helpful to your research. Synthetic Route of 20375-65-9
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2609 – PubChem