Having gained chemical understanding at molecular level, chemistry graduates may choose to apply this knowledge in almost unlimited ways, as it can be used to analyze all matter and therefore our entire environment. Synthetic Route of 53896-49-4
v-Triazolo<1,5-b>pyridazinium salts 5a-c synthesized from alpha-pyridazinyl ketone arylhydrazones and 2,4,4,6-tetrabromocyclohexa-2,5-dien-1-one (TBB) reacted selectively with nucleophiles to yield – besides substituted derivatives 6 – ring-opened cyano compound 9 and/or v-triazoles containing olefinic side chain 10-12.Mechanistic considerations reveal that cation 5 reacts with nucleophiles predominantly at C-7 unless other positions are especially activated.This selectivity proved to be in good agreement with results of semiempirical quantum chemical calculations.
Future efforts will undeniably focus on the diversification of the new catalytic transformations. These may comprise an expansion of the substrate scope from aromatic and heteroaromatic compounds to other hydrocarbons. Keep reading other articles of 53896-49-4, and how the biochemistry of the body works.Synthetic Route of 53896-49-4
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N198 – PubChem