One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C4H5N3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 20744-39-2, Name is Pyridazin-4-amine, molecular formula is C4H5N3
From a high-throughput screen of 42 444 known human kinases inhibitors, a pyrazolo[1,5-b]pyridazine scaffold was identified to begin optimization for the treatment of human African trypanosomiasis. Previously reported data for analogous compounds against human kinases GSK-3beta, CDK-2, and CDK-4 were leveraged to try to improve the selectivity of the series, resulting in 23a which showed selectivity for T. b. brucei over these three human enzymes. In parallel, properties known to influence the absorption, distribution, metabolism, and excretion (ADME) profile of the series were optimized resulting in 20g being progressed into an efficacy study in mice. Though 20g showed toxicity in mice, it also demonstrated CNS penetration in a PK study and significant reduction of parasitemia in four out of the six mice.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Safety of Pyridazin-4-amine, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 20744-39-2
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N147 – PubChem