New explortion of 3,6-Dichloropyridazine

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The specification is heterocyclic compound and including an electron transporting layer are disclosed. (by machine translation)

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1384 – PubChem

 

Extended knowledge of 10344-42-0

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Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. SDS of cas: 10344-42-0. Introducing a new discovery about 10344-42-0, Name is 4-Bromo-3,6-dichloropyridazine

A series of 1,2,4-triazolo[3?,4?:6,1]pyridazino[4,3-e][1,3,4] thiadiazines have been synthesized by intermolecular cyclization of a hydrazide derivative with various triethyl orthoesters. The antibacterial activity of various derivatives of this new heterocyclic system was evaluated. Copyright by Walter de Gruyter.

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Some scientific research about 3,6-Dichloro-4,5-dimethylpyridazine

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We describe an extensive SAR study in the 6-[4-fluoro-3-(substituted)benzyl]-4,5-dimethylpyridazin-3(2H)-one series which led to the identification of potent PARP-1 inhibitors, capable of inhibiting the proliferation of BRCA-1 deficient cancer cells in the low nanomolar range, and displaying >100-fold selectivity over the BRCA wild type counterparts. The series of compounds was devoid of hERG channel activity, and CYP inhibition and induction liabilities. Several analogs were stable in rat and human liver microsomes and displayed moderate rat clearance, with urinary excretion of parent as the major route of elimination.

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Awesome and Easy Science Experiments about 3,6-Dichloropyridazine

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An efficient synthesis of cinchona alkaloid-derived ligands based on solvent-free microwave-assisted reaction was described. The coupling of 1,4-dichlorophthalazine or 3,6-dichloropyridazine with quinine, cinchonine or cinchonidine provide bis- or mono-cinchona alkaloid-derived ligands in moderate to good yields (52-89%) within 15 min under optimum microwave conditions.

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Pyridazine – Wikipedia,
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Awesome and Easy Science Experiments about 6-Methylpyridazin-3-amine

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The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N221 – PubChem

 

The important role of Pyridazine-4,5-diamine

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The present invention relates to an organic light emitting compound which is employed in an organic light emitting device. The compound is represented by chemical formula 1. An organic light emitting device has excellent light emitting properties in driving voltage, luminance, and long lifespan, when the compound is employed as a phosphorescent host compound in a light emitting layer.

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Pyridazine – Wikipedia,
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Discovery of 6-Chloro-N3-methylpyridazine-3,4-diamine

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A continuous process is described for the production of 1,4-cyclohexanedimethanol (CHDM) having a desired or predetermined trans-:cis- isomer ratio by catalytic hydrogenation of a dialkyl 1,4-cyclohexanedicarboxylate in the presence of an ester hydrogenation catalyst. The process is capable of being operated for an extended period of time during which the hydrogenation catalyst declines in catalytic activity and comprises feeding a vaporous mixture of the dialkyl 1,4-cyclohexanedicarboxylate and hydrogen to a hydrogenation zone containing the hydrogenation catalyst and recovering CHDM product. The degree of conversion of the dialkyl 1,4-cyclohexanedicarboxylate at a particular combination of temperature and pressure is related to the trans-:cis- isomer ratio of the CHDM product and may be varied by adjusting at least one feed condition selected from (i) the dialkyl 1,4-cyclohexanedicarboxylate feed rate and (ii) the hydrogen-containing gas:dialkyl 1,4-cyclohexanedicarboxylate molar ratio. As catalyst activity declines during operation of the process over an extended period of time at a particular combination of temperature and pressure, the degree of conversion of the dialkyl 1,4-cyclohexanedicarboxylate and/or the trans-:cis- isomer ratio of the CHDM product may be maintained at a constant value by adjusting at least one of the feed conditions referred to above. The determination of the Actual Activity and Reference Activity of the catalyst and the Actual and Effective Residence Times are included in the hydrogenation process.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N2086 – PubChem

 

Awesome Chemistry Experiments For 141-30-0

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The present invention provides a novel epoxy compound, which can be converted into a cured epoxy resin product having liquid crystal properties by curing with a curing agent. Since the cured epoxy resin product of the present invention exhibits good heat conductivity, it is also useful as an insulating material requiring high heat releasability such as a printed circuit substrate and the like.

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Pyridazine – Wikipedia,
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The important role of 6-Chloro-5-methylpyridazin-3-amine

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The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.

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Pyridazine – Wikipedia,
Pyridazine | C4H4N1069 – PubChem

 

Can You Really Do Chemisty Experiments About Hexahydropyridazine dihydrochloride

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The present invention is directed to novel cytotoxic spliceostatin analogs (I) and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.

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