Discovery of 6-Chloropyridazine-3-carboxylic acid

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5096-73-1, Name is 6-Chloropyridazine-3-carboxylic acid, belongs to pyridazine compound, is a common compound. Computed Properties of C5H3ClN2O2In an article, once mentioned the new application about 5096-73-1.

Pd-N-heterocyclic carbene (NHC)-catalyzed Buchwald-Hartwig animation protocols mediated by Pd-PEPPSI precatalysts is described. These protocols provide access to a range of hindered and functionalized drug-like aryl amines in high yield with both electron-deficient and electron-rich aryl- and heteroaryl chlorides and bromides. Variations in solvent polarity, base and temperature are tolerated, enhancing the scope and utility of this protocol. A mechanistic rationalization for base strength (pKb) requirements is also provided.

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Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2059 – PubChem