2164-61-6, Name is Pyridazine-3-carboxylic acid, belongs to pyridazine compound, is a common compound. COA of Formula: C5H4N2O2In an article, once mentioned the new application about 2164-61-6.
ATG4B or autophagin-1 is a cysteine protease that cleaves ATG8 family proteins. ATG4B plays essential roles in the autophagosome formation and the autophagy pathway. Herein we disclose the design and structural modifications of a series of fluoromethylketone (FMK)-based peptidomimetics as highly potent ATG4B inhibitors. Their structure-activity relationship (SAR) and protease selectivity are also discussed.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N494 – PubChem