Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Computed Properties of C5H6N2O. Introducing a new discovery about 13327-27-0, Name is 6-Methylpyridazin-3(2H)-one
A number of pyridazinone derivatives bearing an arylpiperazinylalkyl chain were synthesized and tested icv in a model of acute nociception induced by thermal stimuli in mice (tail flick). The most interesting and potent compound in this series was 6a, which showed an ED50=3.5 mug, a value about 3-fold higher with respect to morphine by the same route of administration. When administered per os, 6a was 4-fold more potent than morphine in the same test, suggesting a significant bioavailability. The same compound also showed high potency in the hot plate test. The antinociceptive effect of 6a was completely reversed by pretreatment with yohimbine both in the hot plate test and in the tail flick test. This demonstrated the involvement of the adrenergic system, which was confirmed by in vitro radioligand binding studies.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C5H6N2O, you can also check out more blogs about13327-27-0
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N299 – PubChem