Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 3-Hydrazinylpyridazine. Introducing a new discovery about 40972-16-5, Name is 3-Hydrazinylpyridazine
1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 3-Hydrazinylpyridazine, you can also check out more blogs about40972-16-5
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N352 – PubChem