Electric Literature of 88511-47-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.88511-47-1, Name is Pyridazine-4-carboxamide, molecular formula is C5H5N3O. In a Article，once mentioned of 88511-47-1
The modulation of bacterial communication to potentiate the effect of existing antimicrobial drugs is a promising alternative to the development of novel antibiotics. In the present study, we synthesized 58 analogues of hamamelitannin (HAM), a quorum sensing inhibitor and antimicrobial potentiator. These efforts resulted in the identification of an analogue that increases the susceptibility of Staphylococcus aureus towards antibiotics in vitro, in Caenorhabditis elegans, and in a mouse mammary gland infection model, without showing cytotoxicity. Don’t let the bad bugs bite: Staphylococcus aureus (blue) is notorious for causing antibiotic (yellow) resistant biofilm-related infections. The discovery of hamamelitannin as an antimicrobial potentiator led to an investigation of its structure-activity relationship. A potent and metabolically stable analogue (see structure, green) was identified that shows improved activity and drug-like properties.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 88511-47-1, and how the biochemistry of the body works.Electric Literature of 88511-47-1
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N456 – PubChem