Simple exploration of 3,6-Dichloropyridazine

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. category: pyridazine, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 141-30-0, name is 3,6-Dichloropyridazine. In an article,Which mentioned a new discovery about 141-30-0

(Chemical Equation Presented) Microwave irradiation promotes the rapid and efficient reaction of a thiophenol and aryl or heteroaryl halide using a copper or palladium catalyst and a range of ligands, depending upon substrate. Of particular utility is the use of copper(I) iodide (5 mol %) and trans-cyclohexane-1,2-diol as ligand under basic conditions and microwave irradiation to give the corresponding sulfide in high yield. This method for C-S bond formation is applied in the four-step synthesis of the clinical candidate VX-745 in 38% overall yield. The inhibitory activity of VX-745 against p38alpha MAPK is confirmed in Werner syndrome dermal fibroblasts at 1.0 muM concentration by immunoblot assay. 2009 American Chemical Society.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 141-30-0, help many people in the next few years.category: pyridazine

Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N1603 – PubChem