One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 3,6-Dichloro-4,5-dimethylpyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 34584-69-5, Name is 3,6-Dichloro-4,5-dimethylpyridazine, molecular formula is C6H6Cl2N2
The synthesis and pharmacological activity of a series of bicyclic pyrazolo[1,5-alpha]pyrimidines as potent and selective cyclooxygenase-2 (COX-2) inhibitors are described. The new compounds were evaluated both in vitro (COX-1 and COX-2 inhibition in human whole blood) and in vivo (carrageenan-induced paw edema and air-pouch model). Modification of the pyrimidine substituents showed that 6,7-disubstitution provided the best activity and led to the identification of 3-(4-fluorophenyl)-6,7-dimethyl-2-(4-methylsulfonylphenyl) pyrazolo[1,5-alpha]pyrimidine (10f) as one of the most potent and selective COX-2 inhibitor in this series.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 3,6-Dichloro-4,5-dimethylpyridazine, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 34584-69-5, in my other articles.
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2469 – PubChem