Archives for Chemistry Experiments of 1121-79-5

If you are interested in 1121-79-5, you can contact me at any time and look forward to more communication. Formula: C5H5ClN2

Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C5H5ClN2, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 1121-79-5

A potent, in vivo efficacious 11beta hydroxysteroid dehydrogenase type 1 (11beta HSD1) inhibitor (11j) has been identified. Compound 11j inhibited 11beta HSD1 activity in human adipocytes with an IC50 of 4.3?nM and in primary human adipose tissue with an IC80 of 53?nM. Oral administration of 11j to cynomolgus monkey inhibited 11beta HSD1 activity in adipose tissue. Compound 11j exhibited >1000¡Á selectivity over other hydroxysteroid dehydrogenases, displays desirable pharmacodynamic properties and entered human clinical trials in 2011.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N707 – PubChem