14959-32-1, Name is 3-Chloro-6-(methylamino)pyridazine, belongs to pyridazine compound, is a common compound. Recommanded Product: 3-Chloro-6-(methylamino)pyridazineIn an article, once mentioned the new application about 14959-32-1.
2-ARYLBENZOTHIOPHENE DERIVATIVES OR PHARCEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF, AND PHARCEUTICAL COMPOSITION FOR THE DIAGNOSIS OR TREATMENT OF DEGENERATIVE BRAIN DISEASE CONTAINING THE SAME AS ACTIVE INGREDIENT
2-arylbenzothiophene derivatives or pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition for the diagnosis or treatment of degenerative brain disease containing the same as an active ingredient. Since the 2-arylbenzothiophene derivatives of Formula 1 have a relatively high binding affinity for beta-amyloid, they can be used as diagnostic reagents for diagnosing Alzheimer’s disease at an early stage by non-invasive techniques when they are labeled with radioisotopes: wherein R1-R4, V, W, X, Y and Z are as defined in the Detailed Descript of the specification. Further, when the pharmaceutical composition containing the 2-arylbenzothiophene derivative binds with a low-molecular weight beta-amyloid peptide binding compound, generation of malignant high-molecular weight beta-amyloid deposits is minimized. Accordingly, the pharmaceutical composition can be used as a therapeutic agent of degenerative brain disease such as Alzheimer’s disease
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 14959-32-1
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N1025 – PubChem