One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C4H3ClN2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 1120-95-2, Name is 3-Chloropyridazine, molecular formula is C4H3ClN2
Synthesis, radiolabeling and in vivo evaluation of [11C](R)-1- [4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7receptor
In the search for a novel serotonin 7 (5-HT7) receptor PET radioligand we synthesized and evaluated a new series of biphenylpiperazine derivatives in vitro. Among the studied compounds, (R)-1-[4-[2-(4-methoxyphenyl) phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol ((R)-16), showed the best combination of affinity, selectivity, and lipophilicity, and was thus chosen for carbon-11 labelling and evaluation in pigs. After intravenous injection, [11C](R)-16 entered the pig brain and displayed reversible tracer kinetics. Pretreatment with the 5-HT7receptor selective antagonist SB-269970 (1) resulted in limited decrease in the binding of [11C](R)-16, suggesting that this radioligand is not optimal for imaging the brain 5-HT7receptor in vivo but it may serve as a lead compound for the design of novel 5-HT7receptor PET radioligands.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C4H3ClN2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1120-95-2
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N414 – PubChem