One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of 3-Bromo-6-methoxypyridazine, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 17321-29-8, Name is 3-Bromo-6-methoxypyridazine, molecular formula is C5H5BrN2O
Stereospecific Synthesis of E-Alkenes through Anti-Markovnikov Hydroalkylation of Terminal Alkynes
We have developed a method for stereospecific synthesis of E-alkenes from terminal alkynes and alkyl iodides. The hydroalkylation reaction is enabled by a cooperative action of copper and nickel catalysts and proceeds with excellent anti-Markovnikov selectivity. We demonstrate the broad scope of the reaction, which can be accomplished in the presence of esters, nitriles, aryl bromides, ethers, alkyl chlorides, anilines, and a wide range of nitrogen-containing heteroaromatic compounds. Mechanistic studies provide evidence that the copper catalyst activates the alkyne by hydrocupration, which controls both the regio- and diastereoselectivity of the overall reaction. The nickel catalyst activates the alkyl iodide and promotes cross coupling with the alkenyl copper intermediate.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Application In Synthesis of 3-Bromo-6-methoxypyridazine, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 17321-29-8
Reference:
Pyridazine – Wikipedia,
Pyridazine | C4H4N2548 – PubChem