Synthetic Route of 34584-69-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.34584-69-5, Name is 3,6-Dichloro-4,5-dimethylpyridazine, molecular formula is C6H6Cl2N2. In a Article，once mentioned of 34584-69-5
Discovery of NVP-LEQ506, a second-generation inhibitor of smoothened
First disclosure: Continued optimization provided a novel type of Smoothened (Smo) antagonist based on a pyridazine core. The compound, NVP-LEQ506, currently in phaseI clinical trials, combines high intrinsic potency and good pharmacokinetic properties resulting in excellent efficacy in rodent tumor models of medulloblastoma. Activity against a Smo mutant conferring resistance observed in a previous clinical trial with a competitor compound suggests additional therapeutic potential.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 34584-69-5
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2474 – PubChem