One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 5469-70-5, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 5469-70-5, Name is 3-Aminopyridazine, molecular formula is C4H5N3
Synthesis and biological evaluation of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors
A series of 4(5)-(6-alkylpyridin-2-yl)imidazoles 13a-p, 17a, and 17b have been synthesized and evaluated for ALK5 inhibitory activity in an enzyme assay and in cell-based luciferase reporter assays. The quinoxalinyl analogue 13e inhibited ALK5 phosphorylation with an IC50 of 0.012 muM and showed more than 90% inhibition at 0.05 muM in a luciferase reporter assay using HaCaT cells transiently transfected with p3TP-luc reporter construct. The binding mode of 13e generated by flexible docking studies shows that 13e fits well into the active site cavity of ALK5 by forming several tight interactions.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Product Details of 5469-70-5, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 5469-70-5
Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N79 – PubChem