Electric Literature of 20375-65-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 20375-65-9, Name is 3-Phenyl-6-chloropyridazine,introducing its new discovery.
THE CHEMISTRY OF PEPTIDES RELATED TO METABOLITES OF TRICHODERMA SPP. 2. AN IMPROVED METHOD OF CHARACTERIZATION OF PEPTIDES OF 2-METHYLALANINE
4-Chlorobenzoylazide reacts with amino acid and peptide esters to give the 4-chlorobenzoyl derivatives in 60-90percent yield, at room temperature, without measurable racemization.The reaction also proceeds smoothly with hindered amines such as methyl 2-methylalaninate and with secondary amines, e.g. methyl L-prolyl-L-valinate.Ten examples of the reaction are reported with peptides, synthesized for the purpose, that might be accessible from hydrolysates of the numerous fungal metabolites now known, which contain a high proportion of 2-methylalanine.The derivatives of di-, tri-, tetra-, and pentapeptides were highly crystalline, with sharp melting points, and could be detected and integrated in the effluent from chromatography columns at about the 10-ng level.This simple method of derivatization might be usefully applied to the resolution of discrepancies in the physical properties of ostensibly the same 2-methylalanyl peptide prepared in different laboratories.
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Reference：
Pyridazine – Wikipedia,
Pyridazine | C4H4N2740 – PubChem