Electric Literature of 5788-58-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 5788-58-9, 4,5-Dibromopyridazin-3(2H)-one, introducing its new discovery.
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important ?housekeeping? enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 5788-58-9. In my other articles, you can also check out more blogs about 5788-58-9
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N3149 – PubChem