Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 2231-57-4, Name is Carbonothioic dihydrazide, molecular formula is , belongs to pyridazines compound. In a document, author is Akhundova, Fidan N., Application In Synthesis of Carbonothioic dihydrazide.
Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine
New (S)-(1,2,3,6-tetrahydropyridazin-3-yl)methanol was synthesized by Lewis acid catalyzed and self-assembled Diels-Alder (LACASA-DA) cycloaddition reaction using (S)-BINOL as a chiral inductor. The N-2 pyridazine position was protected, the hydroxyl group was carbonylated to form the new bicyclic structure. The protective group was removed and the double bond was dihydroxylated leading to the target compound. Removal of the protective group was performed using a newly found ecofriendly catalyst for N-Boc deprotection. The final iminosugar derivative 7 and all newly synthesized intermediates, were investigated against S. aureus and E. coli bacteria and were found to show promising activity against both gram-positive and gram-negative bacteria.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 2231-57-4, in my other articles. Application In Synthesis of Carbonothioic dihydrazide.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem