In an article, author is Palmioli, Alessandro, once mentioned the application of 2231-57-4, HPLC of Formula: CH6N4S, Name is Carbonothioic dihydrazide, molecular formula is CH6N4S, molecular weight is 106.1501, MDL number is MFCD00007616, category is pyridazines. Now introduce a scientific discovery about this category.
Glyco-functionalized dinuclear rhenium(I) complexes for cell imaging
The design, synthesis and photophysical characterization of four new luminescent glycosylated luminophores based on dinuclear rhenium complexes, namely Glyco-Re, are described. The derivatives have the general formula [Re-2(mu-Cl)(2)(CO)(6)(mu-pydz-R)] (R-pydz = functionalized 1,2-pyridazine), where a sugar residue (R) is covalently bound to the pyridazine ligand in the beta position. Different synthetic pathways have been investigated including the so-called neo-glycorandomization procedure, affording stereoselectively glyco-conjugates containing glucose and maltose in a beta anomeric configuration. A multivalent dinuclear rhenium glycodendron bearing three glucose units is also synthesized. All the Glyco-Re conjugates are comprehensively characterized and their photophysical properties and cellular internalization experiments on human cervical adenocarcinoma (HeLa) cells are reported. The results show that such Glyco-Re complexes display interesting bio-imaging properties, i.e. high cell permeability, organelle selectivity, low cytotoxicity and fast internalization. These findings make the presented Glyco-Re derivatives efficient phosphorescent probes suitable for cell imaging application.
If you are interested in 2231-57-4, you can contact me at any time and look forward to more communication. HPLC of Formula: CH6N4S.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem