Chemistry is an experimental science, Category: pyridazines, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 103-85-5, Name is 1-Phenylthiourea, molecular formula is C7H8N2S, belongs to pyridazines compound. In a document, author is Cetin, Adnan.
A study on synthesis and antimicrobial activity of 4-acyl-pyrazoles
4-Acyl-pyrazole-3-carboxylic acids (1) were synthesized via the reaction of 4-acyl-2,3-furandiones (F) with hydrazone (1-benzylidene-2-(2,5-dimethyl-phenyl)-hydrazine) by heating under solid phase and their acid chlorides (2) were obtained. Then these derivatives were easily converted into the corresponding derivatives such as ester, amide, ureide, pyrazolo-pyridazine, etc. Totally 62 new compounds were synthesized. The structures of these new synthesized compounds were determined by spectroscopic methods and the in vitro antibacterial activity of newly synthesized compounds were carried out against some gram-positive and gram-negative bacteria by well diffusion method (zone inhibition). Our results have showed that these new synthesized compounds have much potent of antibacterial activity owing to containing of pyrazole and/or pyridazine, chromone, oxazine, furane, and pyrrole rings. Some of the new pyrazole derivatives exhibited higher activities than reference drugs against the representative bacteria. (C) 2016 King Saud University. Production and hosting by Elsevier B.V.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 103-85-5, in my other articles. Category: pyridazines.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem