Chemistry, like all the natural sciences, Quality Control of 4-Pyridazinecarboxylic Acid, begins with the direct observation of nature¡ª in this case, of matter.50681-25-9, Name is 4-Pyridazinecarboxylic Acid, SMILES is N1=NC=C(C=C1)C(=O)O, belongs to pyridazines compound. In a document, author is Elissawy, Ahmed M., introduce the new discover.
New secondary metabolites from the mangrove-derived fungus Aspergillus sp. AV-2
Chemical investigation of the mangrove-derived fungus Aspergillus sp. AV-2 following fermentation on solid rice medium led to the isolation of a new phenyl pyridazine derivative (1) and a new prenylated benzaldehyde derivative, dioxoauroglaucin (2), together with fourteen known compounds (3-16). Chemical structures of the new compounds were unambiguously determined based on HRESIMS and extensive 1D and 2D NMR spectroscopic analyses. Compounds 2-7, 8 and 13 were assessed for their antiproliferative activity against Caco-2 cell lines, where flavoglaucin (6) revealed the most potent cytotoxicity with IC50 of 2.87 mu M.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 50681-25-9. Quality Control of 4-Pyridazinecarboxylic Acid.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem