Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 920-66-1, Name is 1,1,1,3,3,3-Hexafluoropropan-2-ol, molecular formula is C3H2F6O, belongs to pyridazines compound, is a common compound. In a patnet, author is Chelini, Alessia, once mentioned the new application about 920-66-1, Recommanded Product: 1,1,1,3,3,3-Hexafluoropropan-2-ol.
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators
LDN-212320 (3) was found to be a potent EAAT2 activator at a translational level, restoring the normal clearance of glutamate and providing neuronal protection. Since the pharmacologic activation of EAAT2 represents a valuable strategy to relieve neuropathic pain, we synthesized novel activators (4a-f) of EAAT2. Among them 4f, analyzed in comparison with 3 by different paradigms in a rat model of oxaliplatin-induced neuropathic pain, showed the better antihypersensitive profile being able to fully counteract the oxaliplatin-induced neuropathy.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 920-66-1. The above is the message from the blog manager. Recommanded Product: 1,1,1,3,3,3-Hexafluoropropan-2-ol.
Reference:
Pyridazine – Wikipedia,
,Pyridazine | C4H4N2 – PubChem