Synthetic Route of 123696-01-5, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 123696-01-5, 5-Methoxypyridazin-3(2H)-one, introducing its new discovery.
A large scale synthesis of 3-chloro-5-methoxypyridazine
A large scale synthesis of 3-chloro-5-methoxypyridazine was developed (18 moles) that relies on the protection of the pyridazinone nitrogen of 4,5-dichloro-3(2H)-pyridazinone as the tetrahydropyranyl derivative 2. The 5-chloro position of the protected pyridazinone was selectively displaced with methoxide to give 3 followed by catalytic hydrogenation of the 4-chloro group to give 4. Removal of the protecting group with acid followed by phosphorous oxychloride treatment gave the target compound 6 in good yield. This route is superior to the previously described synthesis of this compound.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 123696-01-5. In my other articles, you can also check out more blogs about 123696-01-5
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N522 – PubChem