A new application about 141-30-0

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Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of 3,6-Dichloropyridazine, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 141-30-0

Intramolecular fixation of t-butyl groups in thiolactim ethers influencing molecular conformation and the packing behavior

Derived from the result of a previous crystallographic study regarding an ethynylene bridged bispyrimidine, the presence of two intramolecular C-H…N hydrogen bonding contacts being responsible for a fixation of the terminal t-butylthio units to the azine nitrogens was noticed. Acting as stimulus, a series of different pyridine and pyridazine derivatives also featuring this unusual functionality has been synthesized and structurally studied. In order to support the investigations concerning this particular bonding pattern performed via X-ray structure analysis, calculations based on the density functional theory were carried out. It was found that the formation of the intramolecular hydrogen bonding motif has not only impact on the molecular stability but in some cases also predictably influences the reactivity and the packing behavior of the different heterocycles.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1743 – PubChem