141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. Formula: C4H2Cl2N2In an article, once mentioned the new application about 141-30-0.
Pyridazine-derived gamma-secretase modulators
SAR of a novel series of pyridazine-derived gamma-secretase modulators is described. Compound 25 was found to be a potent modulator in vitro, which on further profiling, was found to decrease Abeta42 and Abeta40, and maintain the levels of total Abeta. Furthermore, 25 demonstrated excellent pharmacokinetic parameters as well as good CNS penetration in the rat.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1942 – PubChem