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DERIVATIVES OF 6-SUBSTITUTED TRIAZOLOPYRIDAZ1NES AS REV-ERB AGONISTS
The present invention provides novel 6-substituted [1,2,4]triazolo[4,3-b]pyridazines that are agonists of Rev-Erb. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the activation of Rev-Erb has therapeutic effects, for instance in inflammatory and circadian rhythm-related disorders or cardiometabolic diseases.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: 3,6-Dichloropyridazine, you can also check out more blogs about141-30-0
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1237 – PubChem