Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of 6-Iodopyridazin-3-amine. Introducing a new discovery about 187973-60-0, Name is 6-Iodopyridazin-3-amine
Imidazo[1,2-b]pyridazines. XXI syntheses of some 3-acylaminomethyl-6-(chloro and iodo)-2-(substituted phenyl)-imidazo[1,2-b]pyridazines and -imidazo[1,2-a]pyridines and their interaction with central and mitochondrial benzodiazepine receptors
A series of 3-acylaminomethyl-6-(chloro, iodo and methyl)-2-(phenyl, 4?-t-butylphenyl, 4?-cyclohexyl-phenyl, biphenyl-4?-yl, 4?-chlorophenyl and 4?-iodophenyl)imidazo[1,2-b]pyridazines and imidazo[1,2-a]pyridines has been prepared and examined for interaction with central and mitochondrial (peripheral-type) benzodiazepine receptors. The imidazo[1,2-b]pyridazines were generally more selective for the mitochondrial receptors than the corresponding imidazo[1,2-a]pyridines. Of these compounds, 3-acetamidomethyl-2-(biphenyl-4?-yl)-6-chloroimidazo[1,2-b]pyridazine (9) proved to be the most selective in studies of the displacement of [3H]diazepam from peripheral-type and central benzodiazepine receptors (IC50 2-8 nM and 0% displacement at 1000 nM, respectively).
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of 6-Iodopyridazin-3-amine, you can also check out more blogs about187973-60-0
Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N2940 – PubChem