Archives for Chemistry Experiments of 3,6-Dichloropyridazine

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Chemistry is traditionally divided into organic and inorganic chemistry. category: pyridazine, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 141-30-0

Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates

Compounds useful as schistosomicidal agents are cyclic alkylidenyl N-[6-(R3 R4 N)-4(or 5)-R5 -3-pyridazinyl]aminomethylenemalonates (I), where R3 R4 N is lower-tertiary-amino and R5 is hydrogen or lower-alkyl, are prepared by reacting 3-amino-6-(R3 R4 N)-4(or 5)-R5 -pyridazine (III) with cyclic alkylidenyl alpha-(lower-alkoxymethylene)malonate (IV) or by heating equimolar quantities of III, tri-(lower-alkyl) orthoformate and cyclic alkylidenyl malonate (V). Also shown is cyclic isopropylidenyl N-(6-methylamino-3-pyridazinyl)aminomethylenemalonate, a schistosomicidal agent, and its preparation. Also shown are schistosomicidal compositions comprising as active component a schistosomicidally effective cyclic alkylidenyl N-[6-(R3 R4 N)-4(or 5)-R5 -3-pyridazinyl]aminomethylenemalonate (I) or cyclic isopropylidenyl N-(6-methylamino-3-pyridazinyl)aminomethylenemalonate (II) or salt thereof and a method for the treatment of schistosomiasis which comprises administering to a host infected with schistosomes a schistosomicidally effective amount of said active component.

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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1417 – PubChem