Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Filipski, Kevin J. and a compound is mentioned, 13327-27-0, 6-Methylpyridazin-3(2H)-one, introducing its new discovery. 13327-27-0
A versatile copper-catalyzed coupling reaction of pyridin-2(1H)-ones with aryl halides
A robust method has been developed to couple a wide variety of pyridin-2-ones and aryl halides. This C-N bond forming reaction makes use of catalytic copper(I) iodide and the ligand 8-hydroxyquinoline. These conditions tolerate a wide degree of functionality on both the aryl halide and pyridin-2-one reactants and have resulted in numerous examples being synthesized.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N308 – PubChem