19064-67-6, Name is 6-Chloro-3-hydroxypyridazine, belongs to pyridazine compound, is a common compound. 19064-67-6In an article, authors is Allerton, Charlotte M.N., once mentioned the new application about 19064-67-6.
Design and synthesis of pyridazinone-based 5-HT2C agonists
The SAR of a series of pyridazinone derived 5-HT2C agonists has been explored and resulted in identification of a compound with excellent levels of 5-HT2C functional agonism and selectivity over 5-HT2A and 5-HT2B. This compound displayed good in vivo efficacy in pre-clinical models of stress urinary incontinence, despite having physiochemical properties commensurate with impaired CNS penetration.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N746 – PubChem