141-30-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Giomi, Donatella and a compound is mentioned, 141-30-0, 3,6-Dichloropyridazine, introducing its new discovery.
1-(2-Pyridyl)-2-propen-1-ol: a multipurpose reagent in organic synthesis
A peculiar thermal behaviour of hydroxyallylpyridyl derivatives, likely associated to the weak acidity of the ‘picoline-type’ hydrogen atom and responsible for the formation of allyl inversion products, has been reported. The ‘mobility’ of the same hydrogen atom allowed the unprotected title compound to behave regioselectively as C-1, C-2 or C-3 carbon nucleophile depending on the thermal or base-promoted experimental conditions and on the kind of electrophile; moreover, the corresponding Hantzsch-type pyridine tautomer displayed a biomimetic ability to transfer hydrogen to aromatic and heteroaromatic nitro derivatives.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1705 – PubChem