141-30-0, Name is 3,6-Dichloropyridazine, belongs to pyridazine compound, is a common compound. 141-30-0In an article, authors is Abdou, Wafaa M., once mentioned the new application about 141-30-0.
Synthesis and quantitative structure-activity relationship study of substituted imidazophosphor ester based tetrazolo[1,5-b]pyridazines as antinociceptive/anti-inflammatory agents
A high-yielding general synthesis of imidazophosphor ester based tetrazolo[1,5-b]pyridazines is described. A conjugated reaction between 3,6-diazidopyridazine and different types of phosphonyl carbanion reagents followed by intramolecular cyclization afforded the target products, by using sodium ethanolate solution as a reaction medium. Among the products, five compounds, at a dose of 50 mg per kilogram body weight, showed a notable antinociceptive and anti-inflammatory activity without toxic side-effects.
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Reference£º
Pyridazine – Wikipedia,
Pyridazine | C4H4N1582 – PubChem