5788-58-9,5788-58-9, 4,5-Dibromopyridazin-3(2H)-one is a pyridazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4,5-dibromo-pyridazin-3-one (2.00 g, 7.88 mmol) was dissolved N, N-dimethylformamide (10 mL), potassium carbonate (1.31 g, 9.46 mmol), iodomethane (736 muL, 11.8 mmol) and the mixture was stirred for 2 hours at 50 . The reaction mixture was concentrated under reduced pressure, the residue was diluted with water, and extracted with ethyl acetate. The organic phase was dried anhydrous sodium sulfate and concentrated under reduced pressure, the resulting residue was dissolved in ethyl acetate / methanol was added to give the title compound precipitated solid by filtered and dried (755 mg). Further, to give the title compound (1.20 g) by purifying the residue and the filtrate was concentrated under reduced pressure, and the resulting by silica gel column chromatography.
The synthetic route of 5788-58-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AJINOMOTO COMPANY INCORPORATED; UENO, HIROKAZU; HAYAKAWA, NOBUHIKO; YOKOYAMA, RYOHEI; IWASAKI, KANA; YAMAMOTO, TAKASHI; (67 pag.)JP2016/37467; (2016); A;,
Pyridazine – Wikipedia
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